A study of clinico-mycological profile and treatment of primary otomycosis

نویسندگان

چکیده

Background: Otomycosis is a superficial mycotic infection of the external auditory canal. Clinical presentation, along with otoscopic findings, sufficient to make diagnosis in most cases. Treatment includes aural cleaning followed by instillation anti-fungal ear drops. In recent years, there has been an increasing trend antifungal resistance for commonly used antifungals such as fluconazole and clotrimazole. Drug sensitivity patterns have also shown variability from one region another. Aims Objectives: To evaluate clinico-mycological profile susceptibility pattern treatment outcome primary otomycosis. Materials Methods: A total 230 clinically diagnosed patients otomycosis were included this prospective study. Microbiological causes evaluated KOH wet mount culture samples collected meatus using sterile swabs. Fungal was done on Sabouraud dextrose agar chloramphenicol at 25°C 37°C. Anti-fungal test disk diffusion method medium Muller-Hilton glucose methylene blue. All treated removal fungal debris topical clotrimazole up after 7 days. Non-responders itraconazole. Results: Male-to-female ratio study participants 1:1.3. The frequently observed risk factor oil (20%). Ear itching commonest symptom (70.9%). Positive growth seen 203 (88.3%) Aspergillus present 185 (91.1%) cases, Candida 18 (8.9%) Voriconazole had highest 167 (83.3%) responded (topical Clotrimazole), 36 (16.7%) non-responders. Conclusion: suspected should be positivity, which may further guide selection appropriate agents. Awareness regarding predisposing factors general population result significant drop incidence

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ژورنال

عنوان ژورنال: Asian Journal of Medical Sciences

سال: 2023

ISSN: ['2091-0576']

DOI: https://doi.org/10.3126/ajms.v14i8.54270